Other antidepressants that do not fall strictly under the classifications of SSRIs, TCAs, or MAOIs include the following:
* Buproprion HCL (Wellbutrin®)
* Mitrazapine (Remeron®)
* Nefazadone (Serzone®)
* Trazadone (Desyrel®)
* Venlafaxine (Effexor®)
Venlafaxine (Effexor®) has been shown to cause weight gain but not as severe as has been reported with the SSRIs paroxetine (Paxil®), fuoxetine (Prozac®), and sertraline (Zoloft®).
Mitrazapine (Remeron®) has been associated with significant weight gain, possibly secondary to interactions with the histamine (H1) receptor. It is not associated with gastrointestinal symptoms, sexual dysfunction, or increased heart rate, as seen with the SSRIs.
Trazadone (Desyrel®) is an antidepressant with sedative properties that is frequently used as a sleep aid as well as treatment for depression. It appears to cause less weight gain than amitriptyline (Elavil®) but more than buproprion HCL (Wellbutrin®).
There is currently no information available relating Nefazadone (Serzone®) to increased appetite or weight gain.
Buproprion HCL (Wellbutrin®) has not been associated with weight gain and is commonly used with some success in smoking cessation.
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Related posts:
- Tricyclics Antidepressants
- Tricyclic Antidepressants (TCAs)
- Selective Serotonin Reuptake Inhibitors (SSRIs)
- Anticonvulsants and Mood Stabilizers
- About Antipsychotics
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