Pregnancy. Recent studies have linked Paxil to an increased risk of birth defects, particularly heart defects, when taken during the first trimester of pregnancy. Some of these defects are mild and resolve without intervention, but some may be quite serious. It has also been suggested that exposure to SSRIs during late pregnancy may increase the risk of persistent pulmonary hypertension, a serious lung disorder, in a newborn.
If you are nursing or are pregnant, it is best to discuss the risks and benefits of SSRI therapy with your doctor.
NSAIDs or Aspirin. Use of Paxil with NSAIDs or aspirin may be associated with an increased risk of bleeding.
Liver Disease. Before taking Paxil, tell your doctor if you have impaired liver function. Depending on your condition, your doctor may need to adjust your dose and perform certain tests while on Paxil therapy.
Alcohol. Drinking alcohol with Paxil should be avoided.
This list is not all-inclusive. Other drug interactions should be avoided and medical issues your doctor may need to consider. Be sure to tell your doctor about all medications, including over-the-counter drugs and supplements, you are taking before beginning paroxetine.
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