Injection Could Relieve Chronic Pain For Days

The annual cost of chronic pain in the U.S. is estimated to be $100 billion.

Nearly 5 million people go to their doctors for relief, but meds can wear off and patients run the risk of addiction.

Now, researchers are working on a new approach to chronic pain that comes from an injection.

For Meri Kennedy, every ache is a reminder of a life-long battle with chronic pain, the result of a long list of bad breaks, including fractured ribs, polyps in her vocal chords, breast cancer, a fractured hip and a knee injury.

Meri relies on pain meds to get through the day.

“I am afraid I can get addicted to the pain meds,” she says.

Soon, she may be able to stop the pill popping and get one injection that blocks pain for days.

“We have developed some liposomes, which, when injected either into the tissue or a nerve area, can numb the area for about a week,” says Dr. Dan Kohane, senior associate of critical care at Children’s Hospital in Boston.

Liposomes are specially designed fat-based particles that hold pain meds.

“When injected, liposomes just sit there and let the drugs leave,” says Dr. Kohane.

The liposomes slowly release a potent anesthetic over time. In animal studies, the technique blocked nerves without damaging surrounding cells or muscles.

“The main advantages of this type of formulation over taking a narcotic, for example, to the best of our knowledge these have no addictive potential but can treat the pain,” says Dr. Kohane.

One shot means days of relief

For chronic pain sufferers like Meri, it could turn the chores of daily life into much more pleasant experiences.

The anesthetic used in the study is a toxin naturally found in certain bacteria and puffer fish.

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