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What Other Drugs Will Affect Tramadol?

Friday, March 20th, 2009

You may be more likely to have a seizure (convulsions) if you take Tramadol while you are using certain other medicines. Do not take Tramadol without telling your doctor if you also use any of the following medications:

* an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam); or
* an antidepressant such as amitriptyline (Elavil), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor); paroxetine (Paxil), or sertraline (Zoloft).

Before taking Tramadol, tell your doctor if you also use:

* carbamazepine (Tegretol);
* warfarin (Coumadin);
* digoxin (Lanoxin, Lanoxicaps);
* ketoconazole (Nizoral);
* erythromycin (E-Mycin, E.E.S., Ery-Tab);
* rifampin (Rifadin, Rimactane, Rifater);
* St. John’s wort;
* quinidine (Quinaglute, Quinadex, Cardioquin, Quinora); or
* drugs that make you sleepy (such as cold medicine, other pain medications, muscle relaxants, and medicine for seizures, depression or anxiety).

This list is not complete and there may be other drugs that can interact with Tramadol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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